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Genome-wide quantification of contributions to sexual fitness identifies genes required for spore viability and health in fission yeast
Numerous genes required for sexual reproduction remain to be identified even in simple model species like Schizosaccharomyces pombe. To address this, we developed an assay in S. pombe that couples transposon mutagenesis with high-throughput sequencing (TN-seq) to quantitatively measure the fitness c...
Autores principales: | Billmyre, R. Blake, Eickbush, Michael T., Craig, Caroline J., Lange, Jeffrey J., Wood, Christopher, Helston, Rachel M., Zanders, Sarah E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668190/ https://www.ncbi.nlm.nih.gov/pubmed/36301993 http://dx.doi.org/10.1371/journal.pgen.1010462 |
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