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Repositioning of anti-dengue compounds against SARS-CoV-2 as viral polyprotein processing inhibitor

A therapy for COVID-19 (Coronavirus Disease 19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) remains elusive due to the lack of an effective antiviral therapeutic molecule. The SARS-CoV-2 main protease (M(pro)), which plays a vital role in the viral life cycle, is one of th...

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Detalles Bibliográficos
Autores principales: Bajrai, Leena H., Faizo, Arwa A., Alkhaldy, Areej A., Dwivedi, Vivek Dhar, Azhar, Esam I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668197/
https://www.ncbi.nlm.nih.gov/pubmed/36383621
http://dx.doi.org/10.1371/journal.pone.0277328