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Carbonic anhydrase 4 disruption decreases synaptic and behavioral adaptations induced by cocaine withdrawal

Cocaine use followed by withdrawal induces synaptic changes in nucleus accumbens (NAc), which are thought to underlie subsequent drug-seeking behaviors and relapse. Previous studies suggest that cocaine-induced synaptic changes depend on acid-sensing ion channels (ASICs). Here, we investigated poten...

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Detalles Bibliográficos
Autores principales: Gupta, Subhash C., Ghobbeh, Ali, Taugher-Hebl, Rebecca J., Fan, Rong, Hardie, Jason B., LaLumiere, Ryan T., Wemmie, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668291/
https://www.ncbi.nlm.nih.gov/pubmed/36383659
http://dx.doi.org/10.1126/sciadv.abq5058