CTR9 drives osteochondral lineage differentiation of human mesenchymal stem cells via epigenetic regulation of BMP-2 signaling

Cell fate determination of human mesenchymal stem/stromal cells (hMSCs) is precisely regulated by lineage-specific transcription factors and epigenetic enzymes. We found that CTR9, a key scaffold subunit of polymerase-associated factor complex (PAFc), selectively regulates hMSC differentiation to os...

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Detalles Bibliográficos
Autores principales: Chan, Ngai Ting, Lee, Ming-Song, Wang, Yidan, Galipeau, Jacques, Li, Wan-Ju, Xu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668309/
https://www.ncbi.nlm.nih.gov/pubmed/36383652
http://dx.doi.org/10.1126/sciadv.adc9222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668309/
https://www.ncbi.nlm.nih.gov/pubmed/36383652
http://dx.doi.org/10.1126/sciadv.adc9222

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