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Genetic architecture of natural variation of cardiac performance from flies to humans

Deciphering the genetic architecture of human cardiac disorders is of fundamental importance but their underlying complexity is a major hurdle. We investigated the natural variation of cardiac performance in the sequenced inbred lines of the Drosophila Genetic Reference Panel (DGRP). Genome-wide ass...

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Detalles Bibliográficos
Autores principales: Saha, Saswati, Spinelli, Lionel, Castro Mondragon, Jaime A, Kervadec, Anaïs, Lynott, Michaela, Kremmer, Laurent, Roder, Laurence, Krifa, Sallouha, Torres, Magali, Brun, Christine, Vogler, Georg, Bodmer, Rolf, Colas, Alexandre R, Ocorr, Karen, Perrin, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668334/
https://www.ncbi.nlm.nih.gov/pubmed/36383075
http://dx.doi.org/10.7554/eLife.82459