Nonreceptor Tyrosine Kinase c-Abl-Mediated PHB2 Phosphorylation Aggravates Mitophagy Disorder in Parkinson's Disease Model

Mitophagy and oxidative stress play important roles in Parkinson's disease (PD). Dysregulated mitophagy exacerbates mitochondrial oxidative damage; however, the regulatory mechanism of mitophagy is unclear. Here, we provide a potential mechanistic link between c-Abl, a nonreceptor tyrosine kina...

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Detalles Bibliográficos
Autores principales: Zhang, Yongjiang, Wu, Jiannan, Jin, Weina, Shen, Mengmeng, Yin, Shiyi, Lai, Xiaoyi, Ma, Hongxia, Jiang, Menghan, Sun, Dongxue, Yan, Junqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668474/
https://www.ncbi.nlm.nih.gov/pubmed/36406767
http://dx.doi.org/10.1155/2022/9233749

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668474/
https://www.ncbi.nlm.nih.gov/pubmed/36406767
http://dx.doi.org/10.1155/2022/9233749

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