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Longitudinal microstructural MRI markers of demyelination and neurodegeneration in early relapsing-remitting multiple sclerosis: Magnetisation transfer, water diffusion and g-ratio

INTRODUCTION: Quantitative microstructural MRI, such as myelin-sensitive magnetisation transfer ratio (MTR) or saturation (MTsat), axon-sensitive water diffusion Neurite Orientation Dispersion and Density Imaging (NODDI), and the aggregate g-ratio, may provide more specific markers of white matter i...

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Detalles Bibliográficos
Autores principales: York, Elizabeth N., Meijboom, Rozanna, Thrippleton, Michael J., Bastin, Mark E., Kampaite, Agniete, White, Nicole, Chandran, Siddharthan, Waldman, Adam D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668599/
https://www.ncbi.nlm.nih.gov/pubmed/36265199
http://dx.doi.org/10.1016/j.nicl.2022.103228