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AMPK activator decelerates osteoarthritis development by inhibition of β-catenin signaling in chondrocytes

BACKGROUND: Osteoarthritis (OA) is a common degenerative joint disease with significant negative impact on the quality of life. It has been reported that abnormal upregulation of β-catenin signaling could lead to OA development; however, the upstream regulatory mechanisms of β-catenin signaling have...

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Detalles Bibliográficos
Autores principales: Zhu, Zhenglin, Huang, Yanran, Li, Jun, Yi, Dan, Liao, Junyi, Xiao, Jun, Xiao, Guozhi, Tong, Liping, Huang, Wei, Di, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668625/
https://www.ncbi.nlm.nih.gov/pubmed/36439631
http://dx.doi.org/10.1016/j.jot.2022.10.005