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Adipose-derived stem cell-secreted exosomes enhance angiogenesis by promoting macrophage M2 polarization in type 2 diabetic mice with limb ischemia via the JAK/STAT6 pathway

Diabetic lower limb ischemia is an intractable disease that leads to amputation and even death. Recently, adipose-derived stem cell-secreted exosomes (ADSC-Exo) have been reported as a potential therapeutic approach, but its specific mechanism of action is unknown. Studies have found that exosomes d...

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Detalles Bibliográficos
Autores principales: Wang, Xiangkui, Chen, Shiyuan, Lu, Ran, Sun, Yong, Song, Tao, Nie, Zhonglin, Yu, Chaowen, Gao, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668683/
https://www.ncbi.nlm.nih.gov/pubmed/36406687
http://dx.doi.org/10.1016/j.heliyon.2022.e11495