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Adipose-derived stem cell-secreted exosomes enhance angiogenesis by promoting macrophage M2 polarization in type 2 diabetic mice with limb ischemia via the JAK/STAT6 pathway
Diabetic lower limb ischemia is an intractable disease that leads to amputation and even death. Recently, adipose-derived stem cell-secreted exosomes (ADSC-Exo) have been reported as a potential therapeutic approach, but its specific mechanism of action is unknown. Studies have found that exosomes d...
Autores principales: | Wang, Xiangkui, Chen, Shiyuan, Lu, Ran, Sun, Yong, Song, Tao, Nie, Zhonglin, Yu, Chaowen, Gao, Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668683/ https://www.ncbi.nlm.nih.gov/pubmed/36406687 http://dx.doi.org/10.1016/j.heliyon.2022.e11495 |
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