Broad transcriptomic dysregulation occurs across the cerebral cortex in ASD

Neuropsychiatric disorders classically lack defining brain pathologies, but recent work has demonstrated dysregulation at the molecular level, characterized by transcriptomic and epigenetic alterations(1–3). In autism spectrum disorder (ASD), this molecular pathology involves the upregulation of mic...

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Detalles Bibliográficos
Autores principales: Gandal, Michael J., Haney, Jillian R., Wamsley, Brie, Yap, Chloe X., Parhami, Sepideh, Emani, Prashant S., Chang, Nathan, Chen, George T., Hoftman, Gil D., de Alba, Diego, Ramaswami, Gokul, Hartl, Christopher L., Bhattacharya, Arjun, Luo, Chongyuan, Jin, Ting, Wang, Daifeng, Kawaguchi, Riki, Quintero, Diana, Ou, Jing, Wu, Ye Emily, Parikshak, Neelroop N., Swarup, Vivek, Belgard, T. Grant, Gerstein, Mark, Pasaniuc, Bogdan, Geschwind, Daniel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668748/
https://www.ncbi.nlm.nih.gov/pubmed/36323788
http://dx.doi.org/10.1038/s41586-022-05377-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668748/
https://www.ncbi.nlm.nih.gov/pubmed/36323788
http://dx.doi.org/10.1038/s41586-022-05377-7

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