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Functional biomarkers derived from computed tomography and magnetic resonance imaging differentiate PDAC subgroups and reveal gemcitabine-induced hypo-vascularization

PURPOSE: Pancreatic ductal adenocarcinoma (PDAC) is a molecularly heterogeneous tumor entity with no clinically established imaging biomarkers. We hypothesize that tumor morphology and physiology, including vascularity and perfusion, show variations that can be detected by differences in contrast ag...

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Detalles Bibliográficos
Autores principales: Heid, Irina, Trajkovic-Arsic, Marija, Lohöfer, Fabian, Kaissis, Georgios, Harder, Felix N., Mayer, Moritz, Topping, Geoffrey J., Jungmann, Friderike, Crone, Barbara, Wildgruber, Moritz, Karst, Uwe, Liotta, Lucia, Algül, Hana, Yen, Hsi-Yu, Steiger, Katja, Weichert, Wilko, Siveke, Jens T., Makowski, Marcus R., Braren, Rickmer F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668793/
https://www.ncbi.nlm.nih.gov/pubmed/36074156
http://dx.doi.org/10.1007/s00259-022-05930-6