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Understanding VPAC receptor family peptide binding and selectivity

The vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (PACAP) receptors are key regulators of neurological processes. Despite recent structural data, a comprehensive understanding of peptide binding and selectivity among different subfamily receptors is lacki...

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Detalles Bibliográficos
Autores principales: Piper, Sarah J., Deganutti, Giuseppe, Lu, Jessica, Zhao, Peishen, Liang, Yi-Lynn, Lu, Yao, Fletcher, Madeleine M., Hossain, Mohammed Akhter, Christopoulos, Arthur, Reynolds, Christopher A., Danev, Radostin, Sexton, Patrick M., Wootten, Denise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668914/
https://www.ncbi.nlm.nih.gov/pubmed/36385145
http://dx.doi.org/10.1038/s41467-022-34629-3