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Quantitative PET imaging of the CD4 pool in nonhuman primates

PURPOSE: Previous SPECT and PET semi-quantitative in vivo imaging studies in monkeys have demonstrated specific uptake of radiolabeled rhesus recombinant anti-CD4 monoclonal antibody fragment CD4R1-F(ab΄)(2) in the spleen and clusters of lymph nodes (LNs) but yielded conflicting results of imaging t...

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Detalles Bibliográficos
Autores principales: Kim, Insook, Srinivasula, Sharat, DeGrange, Paula, Long, Brad, Jang, Hyukjin, Carrasquillo, Jorge A., Lane, H. Clifford, Di Mascio, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668939/
https://www.ncbi.nlm.nih.gov/pubmed/36028577
http://dx.doi.org/10.1007/s00259-022-05940-4