Ferroptosis inhibition by deferiprone, attenuates myelin damage and promotes neuroprotection in demyelinated optic nerve

Multiple sclerosis (MS) is a chronic inflammatory disease, which leads to focal demyelination in the brain and spinal cord. Studies showed that iron released during the course of myelin breakdown exacerbates tissue damage, which is in agreement with the features of iron-dependent cell death, ferropt...

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Detalles Bibliográficos
Autores principales: Rayatpour, Atefeh, Foolad, Forough, Heibatollahi, Motahareh, Khajeh, Khosro, Javan, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668997/
https://www.ncbi.nlm.nih.gov/pubmed/36385152
http://dx.doi.org/10.1038/s41598-022-24152-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668997/
https://www.ncbi.nlm.nih.gov/pubmed/36385152
http://dx.doi.org/10.1038/s41598-022-24152-2

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