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Molecular basis for integrin adhesion receptor binding to p21-activated kinase 4 (PAK4)

Integrin adhesion receptors provide links between extracellular ligands and cytoplasmic signaling. Multiple kinases have been found to directly engage with integrin β tails, but the molecular basis for these interactions remain unknown. Here, we assess the interaction between the kinase domain of p2...

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Detalles Bibliográficos
Autores principales: Ha, Byung Hak, Yigit, Sezin, Natarajan, Nalini, Morse, Elizabeth M., Calderwood, David A., Boggon, Titus J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669019/
https://www.ncbi.nlm.nih.gov/pubmed/36385162
http://dx.doi.org/10.1038/s42003-022-04157-3