Multiomics analysis couples mRNA turnover and translational control of glutamine metabolism to the differentiation of the activated CD4(+) T cell

The ZFP36 family of RNA-binding proteins acts post-transcriptionally to repress translation and promote RNA decay. Studies of genes and pathways regulated by the ZFP36 family in CD4(+) T cells have focussed largely on cytokines, but their impact on metabolic reprogramming and differentiation is uncl...

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Detalles Bibliográficos
Autores principales: Matheson, Louise S., Petkau, Georg, Sáenz-Narciso, Beatriz, D’Angeli, Vanessa, McHugh, Jessica, Newman, Rebecca, Munford, Haydn, West, James, Chakraborty, Krishnendu, Roberts, Jennie, Łukasiak, Sebastian, Díaz-Muñoz, Manuel D., Bell, Sarah E., Dimeloe, Sarah, Turner, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669047/
https://www.ncbi.nlm.nih.gov/pubmed/36385275
http://dx.doi.org/10.1038/s41598-022-24132-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669047/
https://www.ncbi.nlm.nih.gov/pubmed/36385275
http://dx.doi.org/10.1038/s41598-022-24132-6

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