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Protein Condensate Formation via Controlled Multimerization of Intrinsically Disordered Sequences

[Image: see text] Many proteins harboring low complexity or intrinsically disordered sequences (IDRs) are capable of undergoing liquid–liquid phase separation to form mesoscale condensates that function as biochemical niches with the ability to concentrate or sequester macromolecules and regulate ce...

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Detalles Bibliográficos
Autores principales: Garabedian, Mikael V., Su, Zhihui, Dabdoub, Jorge, Tong, Michelle, Deiters, Alexander, Hammer, Daniel A., Good, Matthew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669173/
https://www.ncbi.nlm.nih.gov/pubmed/35918061
http://dx.doi.org/10.1021/acs.biochem.2c00250