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Protein Condensate Formation via Controlled Multimerization of Intrinsically Disordered Sequences

[Image: see text] Many proteins harboring low complexity or intrinsically disordered sequences (IDRs) are capable of undergoing liquid–liquid phase separation to form mesoscale condensates that function as biochemical niches with the ability to concentrate or sequester macromolecules and regulate ce...

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Détails bibliographiques
Auteurs principaux: Garabedian, Mikael V., Su, Zhihui, Dabdoub, Jorge, Tong, Michelle, Deiters, Alexander, Hammer, Daniel A., Good, Matthew C.
Format: Online Article Texte
Langue:English
Publié: American Chemical Society 2022
Accès en ligne:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669173/
https://www.ncbi.nlm.nih.gov/pubmed/35918061
http://dx.doi.org/10.1021/acs.biochem.2c00250