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Comparative study on brain pharmacokinetics of Buyang Huanwu Decoction in normal and cerebral ischemia rats using brain microdialysis combined with LC-MS/MS

OBJECTIVE: To conduct a comparative study on the brain pharmacokinetics of seven ingredients (i. e. senkyunolide A, ferulic acid, formononetin, calycosin, ononin, calycosin-O-β-D-glucopyranoside, and paeoniflorin), which were the compounds of Buyang Huanwu Decoction (BHD), in normal and cerebral isc...

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Detalles Bibliográficos
Autores principales: Liu, Wanyi, Zeng, Keqi, Zhou, Xin, Zhang, Yingfeng, Nie, Cong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669359/
https://www.ncbi.nlm.nih.gov/pubmed/36405053
http://dx.doi.org/10.1016/j.chmed.2022.03.007