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Calcium imaging: A versatile tool to examine Huntington’s disease mechanisms and progression

Huntington’s disease (HD) is a fatal, hereditary neurodegenerative disorder that causes chorea, cognitive deficits, and psychiatric symptoms. It is characterized by accumulation of mutant Htt protein, which primarily impacts striatal medium-sized spiny neurons (MSNs), as well as cortical pyramidal n...

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Detalles Bibliográficos
Autores principales: Barry, Joshua, Peng, Allison, Levine, Michael S., Cepeda, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669372/
https://www.ncbi.nlm.nih.gov/pubmed/36408400
http://dx.doi.org/10.3389/fnins.2022.1040113