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Norcantharidin ameliorates estrogen deficient-mediated bone loss by attenuating the activation of extracellular signal-regulated kinase/ROS/NLRP3 inflammasome signaling

Osteoporosis, characterized by reduced bone mass, aberrant bone architecture, and elevated bone fragility, is driven by a disruption of bone homeostasis between bone resorption and bone formation. However, up to now, no drugs are perfect for osteoporosis treatment due to different defects. In this s...

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Detalles Bibliográficos
Autores principales: Yang, Guang, Xu, Huikang, Yao, Minjun, Yan, Shigui, Wu, Mengrui, Zhou, Chenhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669383/
https://www.ncbi.nlm.nih.gov/pubmed/36408264
http://dx.doi.org/10.3389/fphar.2022.1019478