Generation of functionally competent hepatic stellate cells from human stem cells to model liver fibrosis in vitro

The detailed understanding of fibrogenesis has been hampered by a lack of important functional quiescence characteristics and an in vitro model to recapitulate hepatic stellate cell (HSC) activation. In our study, we establish robust endoderm- and mesoderm-sourced quiescent-like induced HSCs (iHSCs)...

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Detalles Bibliográficos
Autores principales: Lai, Xinyuan, Li, Chuanyun, Xiang, Chengang, Pan, Zihang, Zhang, Kai, Wang, Lei, Xie, Bingqing, Cao, Junning, Shi, Jihang, Deng, Juan, Lu, Shichun, Deng, Hongkui, Zhuang, Hui, Li, Tong, Shi, Yan, Xiang, Kuanhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669405/
https://www.ncbi.nlm.nih.gov/pubmed/36270282
http://dx.doi.org/10.1016/j.stemcr.2022.09.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669405/
https://www.ncbi.nlm.nih.gov/pubmed/36270282
http://dx.doi.org/10.1016/j.stemcr.2022.09.010

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