Deciphering the roadmap of in vivo reprogramming toward pluripotency

Differentiated cells can be converted into pluripotent stem cells by expressing the transcription factors OCT4, SOX2, KLF4, and MYC (OSKM) in a process known as reprogramming. Here, using single-cell RNA sequencing of pancreas undergoing reprogramming, we identify markers along the trajectory from a...

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Detalles Bibliográficos
Autores principales: Chondronasiou, Dafni, Martínez de Villarreal, Jaime, Melendez, Elena, Lynch, Cian J., Pozo, Natalia del, Kovatcheva, Marta, Aguilera, Mònica, Prats, Neus, Real, Francisco X., Serrano, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669407/
https://www.ncbi.nlm.nih.gov/pubmed/36270281
http://dx.doi.org/10.1016/j.stemcr.2022.09.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669407/
https://www.ncbi.nlm.nih.gov/pubmed/36270281
http://dx.doi.org/10.1016/j.stemcr.2022.09.009

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