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Plasticity of ocular surface epithelia: Using a murine model of limbal stem cell deficiency to delineate metaplasia and transdifferentiation

Maintaining corneal health and transparency are necessary pre-requisites for exquisite vision, a function ascribed to stem cells (SCs) nestled within the limbus. Perturbations to this site or depletion of its SCs results in limbal SC deficiency. While characterizing a murine model of this disease, w...

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Detalles Bibliográficos
Autores principales: Park, Mijeong, Zhang, Richard, Pandzic, Elvis, Sun, Mingxia, Coulson-Thomas, Vivien J., Di Girolamo, Nick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669409/
https://www.ncbi.nlm.nih.gov/pubmed/36270283
http://dx.doi.org/10.1016/j.stemcr.2022.09.011