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Estimating the sample size of sham-controlled randomized controlled trials using existing evidence

Background: In randomized controlled trials (RCTs), the power is often ‘reverse engineered’ based on the number of participants that can realistically be achieved. An attractive alternative is planning a new trial conditional on the available evidence; a design of particular interest in RCTs that us...

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Detalles Bibliográficos
Autores principales: Siontis, George C.M., Nikolakopoulou, Adriani, Sweda, Romy, Mavridis, Dimitris, Salanti, Georgia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669514/
https://www.ncbi.nlm.nih.gov/pubmed/36451658
http://dx.doi.org/10.12688/f1000research.108554.2