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Estimating the sample size of sham-controlled randomized controlled trials using existing evidence
Background: In randomized controlled trials (RCTs), the power is often ‘reverse engineered’ based on the number of participants that can realistically be achieved. An attractive alternative is planning a new trial conditional on the available evidence; a design of particular interest in RCTs that us...
Autores principales: | Siontis, George C.M., Nikolakopoulou, Adriani, Sweda, Romy, Mavridis, Dimitris, Salanti, Georgia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669514/ https://www.ncbi.nlm.nih.gov/pubmed/36451658 http://dx.doi.org/10.12688/f1000research.108554.2 |
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