The recommended dosage regimen for caspofungin in patients with higher body weight or hypoalbuminaemia will result in low exposure: Five years of data based on a population pharmacokinetic model and Monte-Carlo simulations

Background: To develop a population pharmacokinetic (PPK) model for caspofungin, identify parameters influencing caspofungin pharmacokinetics, and assess the required probability of target attainment (PTA) and cumulative fraction of response (CFR) for various dosing regimens of caspofungin in all pa...

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Detalles Bibliográficos
Autores principales: Yang, Qianting, Zhang, Tao, Zhang, Ying, Sun, Dan, Zheng, Xiaowei, Du, Qian, Wang, Xue, Cheng, Xiaoliang, Xing, Jianfeng, Dong, Yalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669616/
https://www.ncbi.nlm.nih.gov/pubmed/36408257
http://dx.doi.org/10.3389/fphar.2022.993330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669616/
https://www.ncbi.nlm.nih.gov/pubmed/36408257
http://dx.doi.org/10.3389/fphar.2022.993330

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