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Elevated Ca(2+) at the triad junction underlies dysregulation of Ca(2+) signaling in dysferlin-null skeletal muscle
Dysferlin-null A/J myofibers generate abnormal Ca(2+) transients that are slightly reduced in amplitude compared to controls. These are further reduced in amplitude by hypoosmotic shock and often appear as Ca(2+) waves (Lukyanenko et al., J. Physiol., 2017). Ca(2+) waves are typically associated wit...
Autores principales: | Lukyanenko, Valeriy, Muriel, Joaquin, Garman, Daniel, Breydo, Leonid, Bloch, Robert J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669649/ https://www.ncbi.nlm.nih.gov/pubmed/36406982 http://dx.doi.org/10.3389/fphys.2022.1032447 |
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