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Integrated analysis of the genomic and transcriptional profile of gliomas with isocitrate dehydrogenase-1 and tumor protein 53 mutations

Background: The gene mutation of isocitrate dehydrogenase-1 (IDH1) is commonly found in LGG and some GBM patients and usually carries tumor protein 53 (TP53) mutations. However, the underlying mechanisms on both mutations of glioma patients in IDH1 and TP53 are still unclear. Aim: To find the potent...

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Detalles Bibliográficos
Autores principales: Liu, Han-Qing, Li, Wei-Xin, An, Ya-Wen, Wu, Tao, Jiang, Guang-Yu, Dong, Yu, Chen, Wei-Xin, Wang, Jian-Chun, Wang, Cheng, Song, Shuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669701/
https://www.ncbi.nlm.nih.gov/pubmed/36377597
http://dx.doi.org/10.1177/03946320221139262