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Analysis of MRE11 and Mortality Among Adults With Muscle-Invasive Bladder Cancer Managed With Trimodality Therapy

IMPORTANCE: Bladder-preserving trimodality therapy can be an effective alternative to radical cystectomy for treatment of muscle-invasive bladder cancer (MIBC), but biomarkers are needed to guide optimal patient selection. The DNA repair protein MRE11 is a candidate response biomarker that has not b...

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Detalles Bibliográficos
Autores principales: Magliocco, Anthony M., Moughan, Jennifer, Miyamoto, David T., Simko, Jeff, Shipley, William U., Gray, Phillip J., Hagan, Michael P., Parliament, Matthew, Tester, William J., Zietman, Anthony L., McCarthy, Susan, Saeed-Vafa, Daryoush, Xiong, Yin, Ayral, Taylor, Hartford, Alan C., Patel, Ashish, Rosenthal, Seth A., Chafe, Susan, Greenberg, Richard, Schwartz, Michael A., Augspurger, Mark E., Keech, John A., Winter, Kathryn A., Feng, Felix Y., Efstathiou, Jason A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669810/
https://www.ncbi.nlm.nih.gov/pubmed/36383379
http://dx.doi.org/10.1001/jamanetworkopen.2022.42378