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Eupatilin attenuates the senescence of nucleus pulposus cells and mitigates intervertebral disc degeneration via inhibition of the MAPK/NF-κB signaling pathway

Intervertebral disc degeneration (IDD) is the main cause of low back pain. An increasing number of studies have suggested that inflammatory response or the senescence of nucleus pulposus (NP) cells is strongly associated with the progress of IDD. Eupatilin, the main flavonoid extracted from Artemisi...

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Detalles Bibliográficos
Autores principales: Yang, Huan, Yang, Xiao, Rong, Kewei, Liang, Jiarong, Wang, Zhengting, Zhao, Jie, Zhang, Pu, Li, Yijie, Wang, Lihuan, Ma, Hui, Ye, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669913/
https://www.ncbi.nlm.nih.gov/pubmed/36408239
http://dx.doi.org/10.3389/fphar.2022.940475