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Multi-omics analysis reveals neuroinflammation, activated glial signaling, and dysregulated synaptic signaling and metabolism in the hippocampus of aged mice

Aging is an intricate biological event that occurs in both vertebrates and invertebrates. During the aging process, the brain, a vulnerable organ, undergoes structural and functional alterations, resulting in behavioral changes. The hippocampus has long been known to be critically associated with co...

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Detalles Bibliográficos
Autores principales: Lu, Yinzhong, Xu, Kejia, Lin, Dongyang, Wang, Shuyan, Fu, Rao, Deng, Xiaobei, Croppi, Giorgia, Zhang, Junjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669972/
https://www.ncbi.nlm.nih.gov/pubmed/36408109
http://dx.doi.org/10.3389/fnagi.2022.964429