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Fast peptide exchange on major histocompatibility complex class I molecules by acidic stabilization of a peptide‐empty intermediate

The cell biology and biochemistry of peptide exchange on major histocompatibility complex class I (MHC‐I) proteins are of great interest in the study of immunodominance, which requires iterative optimization of peptide affinity, and cross‐presentation of pathogen and tumor antigens, in which endogen...

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Detalles Bibliográficos
Autores principales: Saikia, Ankur, Hadeler, Andries, Prasad, Pranathi, Zacharias, Martin, Springer, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669992/
https://www.ncbi.nlm.nih.gov/pubmed/36258668
http://dx.doi.org/10.1002/pro.4478