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Experimentally Induced Anti-Myeloperoxidase Vasculitis Is Not Attenuated in Factor B or VISTA Deficient Mice

BACKGROUND: Anti-neutrophil cytoplasmic antibody vasculitis is characterized by antibodies to myeloperoxidase or proteinase 3. Previous work in murine anti-myeloperoxidase vasculitis has shown a role for the alternative pathway complement component factor B and the anaphylatoxin C5a. However, mice d...

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Detalles Bibliográficos
Autores principales: Flórez-Barrós, Fernanda, Freeley, Simon J., Tham, El Li, Robson, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670022/
https://www.ncbi.nlm.nih.gov/pubmed/36751530
http://dx.doi.org/10.1159/000521233