Causes of Industrial Protein A Column Degradation, Explored Using Raman Spectroscopy

[Image: see text] Monoclonal antibodies (mAbs) are used extensively as biotherapeutics for chronic and acute conditions. Production of mAbs is lengthy and expensive, with protein A affinity capture the most costly step, due both to the nature of the resin and its marked reduction in binding capacity...

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Detalles Bibliográficos
Autores principales: Beattie, James W., Istrate, Alena, Lu, Annabelle, Marshall, Cameron, Rowland-Jones, Ruth C., Farys, Monika, Kazarian, Sergei G., Byrne, Bernadette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670029/
https://www.ncbi.nlm.nih.gov/pubmed/36318727
http://dx.doi.org/10.1021/acs.analchem.2c03063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670029/
https://www.ncbi.nlm.nih.gov/pubmed/36318727
http://dx.doi.org/10.1021/acs.analchem.2c03063

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