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Causes of Industrial Protein A Column Degradation, Explored Using Raman Spectroscopy
[Image: see text] Monoclonal antibodies (mAbs) are used extensively as biotherapeutics for chronic and acute conditions. Production of mAbs is lengthy and expensive, with protein A affinity capture the most costly step, due both to the nature of the resin and its marked reduction in binding capacity...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670029/ https://www.ncbi.nlm.nih.gov/pubmed/36318727 http://dx.doi.org/10.1021/acs.analchem.2c03063 |