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Exploring the pathogenesis of age-related macular degeneration: A review of the interplay between retinal pigment epithelium dysfunction and the innate immune system

Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss in the older population. Classical hallmarks of early and intermediate AMD are accumulation of drusen, a waste deposit formed under the retina, and pigmentary abnormalities in the retinal pigment epithelium (RPE)....

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Detalles Bibliográficos
Autores principales: Wong, Josephine H. C., Ma, Jessica Y. W., Jobling, Andrew I., Brandli, Alice, Greferath, Ursula, Fletcher, Erica L., Vessey, Kirstan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670140/
https://www.ncbi.nlm.nih.gov/pubmed/36408381
http://dx.doi.org/10.3389/fnins.2022.1009599