Cargando…
Exploring the pathogenesis of age-related macular degeneration: A review of the interplay between retinal pigment epithelium dysfunction and the innate immune system
Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss in the older population. Classical hallmarks of early and intermediate AMD are accumulation of drusen, a waste deposit formed under the retina, and pigmentary abnormalities in the retinal pigment epithelium (RPE)....
Autores principales: | Wong, Josephine H. C., Ma, Jessica Y. W., Jobling, Andrew I., Brandli, Alice, Greferath, Ursula, Fletcher, Erica L., Vessey, Kirstan A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670140/ https://www.ncbi.nlm.nih.gov/pubmed/36408381 http://dx.doi.org/10.3389/fnins.2022.1009599 |
Ejemplares similares
-
Treatments targeting autophagy ameliorate the age-related macular degeneration phenotype in mice lacking APOE (apolipoprotein E)
por: Vessey, Kirstan A, et al.
Publicado: (2022) -
Dorsal-Ventral Differences in Retinal Structure in the Pigmented Royal College of Surgeons Model of Retinal Degeneration
por: Greferath, Una, et al.
Publicado: (2021) -
Inner retinal change in a novel rd1-FTL mouse model of retinal degeneration
por: Greferath, Ursula, et al.
Publicado: (2015) -
Studying Age-Related Macular Degeneration Using Animal Models
por: Fletcher, Erica L., et al.
Publicado: (2014) -
Photoreceptor Degeneration in Pro23His Transgenic Rats (Line 3) Involves Autophagic and Necroptotic Mechanisms
por: Kakavand, Kiana, et al.
Publicado: (2020)