A common variant in the hepatobiliary phospholipid transporter ABCB4 modulates liver injury in PBC but not in PSC: prospective analysis in 867 patients

BACKGROUND: The ATP-binding cassette subfamily B member 4 (ABCB4) gene encodes the hepatic phospholipid transporter. Variants in the ABCB4 gene are associated with various cholestatic phenotypes, some of which progress to liver fibrosis and cirrhosis. The aim of our study was to investigate the role...

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Detalles Bibliográficos
Autores principales: Kruk, Beata, Milkiewicz, Malgorzata, Raszeja-Wyszomirska, Joanna, Milkiewicz, Piotr, Krawczyk, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670364/
https://www.ncbi.nlm.nih.gov/pubmed/36397154
http://dx.doi.org/10.1186/s13023-022-02565-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670364/
https://www.ncbi.nlm.nih.gov/pubmed/36397154
http://dx.doi.org/10.1186/s13023-022-02565-6

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