Cargando…
A common variant in the hepatobiliary phospholipid transporter ABCB4 modulates liver injury in PBC but not in PSC: prospective analysis in 867 patients
BACKGROUND: The ATP-binding cassette subfamily B member 4 (ABCB4) gene encodes the hepatic phospholipid transporter. Variants in the ABCB4 gene are associated with various cholestatic phenotypes, some of which progress to liver fibrosis and cirrhosis. The aim of our study was to investigate the role...
Autores principales: | Kruk, Beata, Milkiewicz, Malgorzata, Raszeja-Wyszomirska, Joanna, Milkiewicz, Piotr, Krawczyk, Marcin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670364/ https://www.ncbi.nlm.nih.gov/pubmed/36397154 http://dx.doi.org/10.1186/s13023-022-02565-6 |
Ejemplares similares
-
PNPLA3 p.I148M and TM6SF2 p.E167K variants do not predispose to liver injury in cholestatic liver diseases: A prospective analysis of 178 patients with PSC
por: Kruk, Beata, et al.
Publicado: (2018) -
Heterozygous Inactivation of the Nuclear Receptor PXR/NR1I2 in a Patient With Anabolic Steroid-Induced Intrahepatic Cholestasis
por: Liebe, Roman, et al.
Publicado: (2016) -
Vitamin D Receptor Polymorphisms Predispose to Primary Biliary Cirrhosis and Severity of the Disease in Polish Population
por: Kempińska-Podhorecka, Agnieszka, et al.
Publicado: (2012) -
Ferroportin-related haemochromatosis associated with novel Y64H mutation of the SCL40A1 gene
por: Raszeja-Wyszomirska, Joanna, et al.
Publicado: (2014) -
TRAF1-C5 Affects Quality of Life in Patients with Primary Biliary Cirrhosis
por: Raszeja-Wyszomirska, Joanna, et al.
Publicado: (2013)