Landscape of immune-related signatures induced by targeting of different epigenetic regulators in melanoma: implications for immunotherapy

BACKGROUND: Improvement of efficacy of immune checkpoint blockade (ICB) remains a major clinical goal. Association of ICB with immunomodulatory epigenetic drugs is an option. However, epigenetic inhibitors show a heterogeneous landscape of activities. Analysis of transcriptional programs induced in...

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Detalles Bibliográficos
Autores principales: Anichini, Andrea, Molla, Alessandra, Nicolini, Gabriella, Perotti, Valentina Eleonora, Sgambelluri, Francesco, Covre, Alessia, Fazio, Carolina, Lofiego, Maria Fortunata, Di Giacomo, Anna Maria, Coral, Sandra, Manca, Antonella, Sini, Maria Cristina, Pisano, Marina, Noviello, Teresa, Caruso, Francesca, Brich, Silvia, Pruneri, Giancarlo, Maurichi, Andrea, Santinami, Mario, Ceccarelli, Michele, Palmieri, Giuseppe, Maio, Michele, Mortarini, Roberta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670381/
https://www.ncbi.nlm.nih.gov/pubmed/36397155
http://dx.doi.org/10.1186/s13046-022-02529-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670381/
https://www.ncbi.nlm.nih.gov/pubmed/36397155
http://dx.doi.org/10.1186/s13046-022-02529-5

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