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Landscape of immune-related signatures induced by targeting of different epigenetic regulators in melanoma: implications for immunotherapy
BACKGROUND: Improvement of efficacy of immune checkpoint blockade (ICB) remains a major clinical goal. Association of ICB with immunomodulatory epigenetic drugs is an option. However, epigenetic inhibitors show a heterogeneous landscape of activities. Analysis of transcriptional programs induced in...
Autores principales: | Anichini, Andrea, Molla, Alessandra, Nicolini, Gabriella, Perotti, Valentina Eleonora, Sgambelluri, Francesco, Covre, Alessia, Fazio, Carolina, Lofiego, Maria Fortunata, Di Giacomo, Anna Maria, Coral, Sandra, Manca, Antonella, Sini, Maria Cristina, Pisano, Marina, Noviello, Teresa, Caruso, Francesca, Brich, Silvia, Pruneri, Giancarlo, Maurichi, Andrea, Santinami, Mario, Ceccarelli, Michele, Palmieri, Giuseppe, Maio, Michele, Mortarini, Roberta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670381/ https://www.ncbi.nlm.nih.gov/pubmed/36397155 http://dx.doi.org/10.1186/s13046-022-02529-5 |
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