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HMOX1 STR polymorphism and malaria: an analysis of a large clinical dataset

BACKGROUND: Inducible expression of heme oxygenase-1 (encoded by the gene HMOX1) may determine protection from heme released during malaria infections. A variable length, short tandem GT(n) repeat (STR) in HMOX1 that may influence gene expression has been associated with outcomes of human malaria in...

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Detalles Bibliográficos
Autores principales: Hamilton, Fergus, Mitchell, Ruth, Cunnington, Aubrey, Ghazal, Peter, Timpson, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670449/
https://www.ncbi.nlm.nih.gov/pubmed/36397106
http://dx.doi.org/10.1186/s12936-022-04352-x