Cargando…

TREM2 and microglia exosomes: a potential highway for pathological tau

Tau pathology appears to spread along neuronal networks via the template misfolding of tau by pathological tau conformations. The mechanisms underlying neuron-to-neuron transmission of tau are unclear and recent work demonstrates a role for microglia in the spread of tau pathology. In this Commentar...

Descripción completa

Detalles Bibliográficos
Autores principales: Jain, Nimansha, Ulrich, Jason D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670492/
https://www.ncbi.nlm.nih.gov/pubmed/36397070
http://dx.doi.org/10.1186/s13024-022-00581-5