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Identification of risk variants related to malignant tumors in children with birth defects by whole genome sequencing

BACKGROUND: Children with birth defects (BD) are more likely to develop cancer and the increased risk of cancer persists into adulthood. Prior population-based assessments have demonstrated that even non-chromosomal BDs are associated with at least two-fold increase of cancer risk. Identification of...

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Detalles Bibliográficos
Autores principales: Liu, Yichuan, Qu, Hui-Qi, Chang, Xiao, Mentch, Frank D, Qiu, Haijun, Nguyen, Kenny, Wang, Xiang, Saeidian, Amir Hossein, Watson, Deborah, Glessner, Joseph, Hakonarson, Hakon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670520/
https://www.ncbi.nlm.nih.gov/pubmed/36384586
http://dx.doi.org/10.1186/s40364-022-00431-y