Hypoxia increases RCC stem cell phenotype via altering the androgen receptor (AR)-lncTCFL5-2-YBX1-SOX2 signaling axis

BACKGROUND: Early studies indicated that the androgen receptor (AR) could promote renal cell carcinoma (RCC) development and metastasis, but its linkage to RCC progression under hypoxia, remains unclear. RESULTS: Here we found AR expression in RCC cells decreased in response to hypoxia, which might...

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Detalles Bibliográficos
Autores principales: Guo, Changcheng, Sun, Yin, Zhai, Wei, Yao, Xudong, Gong, Dongkui, You, Bosen, Huang, Chi-Ping, Zheng, Junhua, Chang, Chawnshang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670551/
https://www.ncbi.nlm.nih.gov/pubmed/36397101
http://dx.doi.org/10.1186/s13578-022-00912-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670551/
https://www.ncbi.nlm.nih.gov/pubmed/36397101
http://dx.doi.org/10.1186/s13578-022-00912-5

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