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Formation of Protamine and Zn–Insulin Assembly: Exploring Biophysical Consequences
[Image: see text] The insulin–protamine interaction is at the core of the mode of action in many insulin formulations (Zn + insulin + protamine) and to treat diabetes, in which protamine is added to the stable form of hexameric insulin (Zn–insulin). However, due to the unavailability of quantitative...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670714/ https://www.ncbi.nlm.nih.gov/pubmed/36406544 http://dx.doi.org/10.1021/acsomega.2c04419 |