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Formation of Protamine and Zn–Insulin Assembly: Exploring Biophysical Consequences

[Image: see text] The insulin–protamine interaction is at the core of the mode of action in many insulin formulations (Zn + insulin + protamine) and to treat diabetes, in which protamine is added to the stable form of hexameric insulin (Zn–insulin). However, due to the unavailability of quantitative...

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Detalles Bibliográficos
Autores principales: Aggarwal, Soumya, Tanwar, Neetu, Singh, Ankit, Munde, Manoj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670714/
https://www.ncbi.nlm.nih.gov/pubmed/36406544
http://dx.doi.org/10.1021/acsomega.2c04419