Recent Advances of DprE1 Inhibitors against Mycobacterium tuberculosis: Computational Analysis of Physicochemical and ADMET Properties

[Image: see text] Decaprenylphosphoryl-β-d-ribose 2′-epimerase (DprE1) is a critical flavoenzyme in Mycobacterium tuberculosis, catalyzing a vital step in the production of lipoarabinomannan and arabinogalactan, both of which are essential for cell wall biosynthesis. Due to its periplasmic localizat...

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Detalles Bibliográficos
Autores principales: Amado, Patrícia S. M., Woodley, Christopher, Cristiano, Maria L. S., O’Neill, Paul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670723/
https://www.ncbi.nlm.nih.gov/pubmed/36406587
http://dx.doi.org/10.1021/acsomega.2c05307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670723/
https://www.ncbi.nlm.nih.gov/pubmed/36406587
http://dx.doi.org/10.1021/acsomega.2c05307

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