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Region-Specific Enhancement of c-fos Expression by Combined Treatment With NMDA Receptor Agonists and Antagonists With Antidepressant Potential

Rapastinel, formerly Glyx-13, is a novel positive allosteric modulator of the N-methyl-D-aspartate-receptor (NMDAR) that counteracts psychotomimetic actions of NMDAR antagonists. We set out to evaluate the effect of rapastinel alone or in combination with the global and GluN2B subunit–specific NMDAR...

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Detalles Bibliográficos
Autores principales: Vasilescu, Andrei-Nicolae, Pfeiffer, Natascha, Terraneo, Federica, Riva, Marco Andrea, Lang, Undine E, Inta, Dragos, Gass, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670745/
https://www.ncbi.nlm.nih.gov/pubmed/35974297
http://dx.doi.org/10.1093/ijnp/pyac051